interactive_tool · nmn_dosing
NMN Dosage Calculator (by Body Weight)
Most “NMN dose by weight” calculators hand you a per-kilogram number that is extrapolated from mouse studies and wrong by more than ten-fold. This one is honest: it shows the flat, evidence-based dose the human trials actually used, and then uses your weight to demonstrate exactly why the per-kg math misleads. It is education, not a dose recommendation.
read_before_use
This is an educational estimate, not medical advice. NMN is a dietary supplement with limited long-term human safety data — most trials ran weeks to a few months, not years. There is no established weight-based dose: the human studies used flat doses, and more is not proven better (the rise in blood NAD+ plateaus, and raising NAD+ is not the same as a felt health benefit). Do not treat any number here as a target. Talk to a licensed clinician before starting, stopping, or changing any supplement — especially if you take medications, are pregnant or nursing, or have a medical condition.
evidence_based_dose · flat · typical
250–500mg / day
This is a flat dose taken from the human trials — the same milligrams whether you weigh 60 kg or 100 kg. Most human evidence sits at 250 mg/day, with safety shown up to a single 1,250 mg dose. More is not proven better.
per_kg_comparison · for 70 kg
- Naive mg/kg calculator
- ~21,000 mg
- 300 mg/kg × 70 kg — over 42× too high
- Corrected (surface area)
- ~1,700 mg
- 300 ÷ 12.3 ≈ 24 mg/kg × 70 kg
- What trials used
- 250–500 mg
- flat dose · not by body weight
Read the columns left to right. The per-kg calculators you find online take the mouse longevity dose (~300 mg/kg) and multiply it by your weight — which overshoots reality by more than ten-fold. Correct pharmacology scales an animal dose down by a body-surface-area factor (÷~12.3 for mice), landing near ~24 mg/kg. But the human trials skipped weight-based dosing entirely and used flat doses — most often 250 mg/day. That flat number is the one to anchor to.
read_the_evidence
A number is the easy part. Whether NMN does anything for you, when to take it, and whether it is safe with your medications is what actually matters — start here:
This calculator is informational and not medical advice. It does not account for your individual health, medications, or circumstances, and it deliberately does not provide a weight-personalized dose because the human evidence does not support one. NMN is a supplement, not an FDA-approved drug, and its long-term safety in humans is not established. Talk to a licensed clinician before acting on any figure here.