Best NAD+ Therapy Providers (2026): Doctor-Reviewed, Ranked
NAD+ is a coenzyme central to cellular energy that a growing number of telehealth clinics now offer as an injection, IV, nasal spray, or oral protocol. We compared the providers that actually offer it on the things that matter once the marketing fades: a transparent price, genuine clinical review, and real human support. CoreAge Rx earns our top spot for value — a flat $93/month with doctor-reviewed protocols, 503A compounding, and included nurse and dietitian consults.
// written by Marcus Hale·Longevity Research Editor ·last_updated=
FTC disclosure. The NAD Review holds affiliate or referral partnerships with some — not all of the providers ranked on this page, and may earn a commission at no extra cost to you when you start treatment through one of our links. Like any comparison site, that compensation can influence which provider we feature and how prominently it sits up top. Providers we have no commercial tie to still earn their place on the merits — and we link out to them too; they simply do not get the same promotional emphasis. The order itself is set by our own ranking factors — price transparency, clinical oversight, and support — never by a partnership: a commission does not buy a higher rank. See our full disclosure.
// rank_01 · top_pick
$93 / month, flat
1
CoreAge Rx
Doctor-reviewed NAD+ with a flat monthly price and built-in human support.
Featured partner · #1
$93 / month, flat
U.S.-licensed clinicians review an online intake; the NAD+ protocol is filled by a 503A compounding pharmacy. CoreAge offers both an NAD+ injection and an NAD+ nasal spray ("Hello Energy"), each at a flat $93/month. Every plan includes 1:1 consults with nurses and registered dietitians, an automatic refund if you are not approved, and roughly 2-business-day shipping after approval. Monthly recurring, with no separate membership or lab fee.
Strengths
Transparent flat $93/month — no separate membership, lab, or hidden fees
Doctor-reviewed protocols filled by a 503A compounding pharmacy
Two formats at the same price: NAD+ injection and NAD+ nasal spray
Included 1:1 support from nurses and registered dietitians
Automatic refund if you are not approved for treatment
Trade-offs
Single-category focus — not a full hormone-optimization clinic
Like all compounded NAD+, it is not an FDA-approved product, and injectable/nasal NAD+ has no rigorous trial evidence (see our evidence review)
Real providers that verifiably offer an NAD+ program — at-home injection and nasal telehealth, clinic and mobile IV, and the best-evidenced oral NR precursors — each checked against their own site in 2026. We only state a price where the provider published one we could confirm.
2
HydraMed
Higher flat monthly price with a free intake consult and no membership.
$299 / month (or $369 one-time), 1000 mg vial
Online intake with a licensed provider; once approved, compounded NAD+ (a 1000 mg, 5 mL vial) ships from the pharmacy. The plan is flat — no membership tier — and bundles a free online consultation, free shipping, and virtual support, with a cheaper one-time option for a single vial.
Strengths
Genuinely flat monthly price with no separate membership
Free online consultation and shipping included; one-time purchase option available
Trade-offs
Substantially higher than CoreAge's $93/month
Single injection format; no included nurse or dietitian program
Visit HydraMed ↗Shown for honest comparison · verified on the provider's own site in 2026
3
AgelessRx
Broad longevity-telehealth menu; NAD+ as an at-home injection, nasal spray, or patch.
Injection from $185/month; nasal from $125; patch from $160
A longevity-focused telehealth clinic with a real questionnaire → prescriber-review → Rx flow. NAD+ is offered as a self-administered subcutaneous injection (from about $185/month), an intranasal spray (from about $125), or a battery-powered iontophoresis patch (from about $160). It sits alongside a wider cash-pay longevity menu (metformin, low-dose naltrexone, rapamycin). Pricing varies by product and dose; there is no insurance billing.
Strengths
Genuine U.S.-licensed prescriber review with a clear intake-to-Rx flow
Multiple NAD+ formats (injection, nasal, patch) under one established clinic
Trade-offs
Injection start price is roughly double CoreAge's flat $93, and varies by dose
Nasal and patch absorption claims are unproven — see our evidence review
Cash-pay only; no included nurse or dietitian program
Visit AgelessRx ↗Shown for honest comparison · verified on the provider's own site in 2026
4
Invigor Medical
Established telehealth clinic; NAD+ priced higher with consult and supplies bundled.
Starting at $340 / month (includes doctor consult and supplies)
Virtual visit with a licensed provider, then NAD+ plus injection supplies shipped to your door, prescribed 100% online by U.S. doctors. The advertised price bundles the consult and supplies; Invigor publicly names its compounding-pharmacy partners.
Strengths
Consult and injection supplies bundled into the advertised price
Long-running telehealth clinic that openly names its pharmacy partners
Trade-offs
Starting price is well above CoreAge's flat $93
Pricing can vary by dose; an upfront initial-order fee has been reported elsewhere
Visit Invigor Medical ↗Shown for honest comparison · verified on the provider's own site in 2026
5
Hone Health
Lab-gated optimization platform that prices NAD+ on top of a recurring membership.
Hone is a biomarker-driven optimization platform. NAD+ injections require an initial lab panel (discounted to $65) and a physician video consult, then are billed at $165/month on top of an ongoing membership ($25/month Basic or $155/month Premium). The medication price alone does not reflect the true monthly cost.
Strengths
Baseline and ongoing lab testing for users who want data-driven monitoring
Physician video consult and a personalized plan included with onboarding
Trade-offs
Stacked cost: the $165 medication is charged on top of a recurring membership
Lab-gated onboarding is heavier than a single-product NAD+ plan
Total monthly outlay can far exceed CoreAge once membership and labs are added
Visit Hone Health ↗Shown for honest comparison · verified on the provider's own site in 2026
6
Drip Hydration
Multi-city mobile NAD+ IV drips and at-home injection kits — premium, per-session pricing.
NAD+ IV roughly $799–$999 per session; memberships higher
A large multi-city mobile-IV operator that brings a nurse to your home or office for an NAD+ drip (typically 250–1000 mg over 1–2 hours), and also sells self-administered injection kits. This is the clinic-grade IV experience rather than a flat monthly telehealth plan, with per-session pricing that runs far above an at-home injection subscription.
Strengths
Nurse-administered, in-home IV from an established national operator
Higher per-session doses than a typical at-home subcutaneous injection
Long chair time, and injection-kit pricing is not clearly published
IV NAD+ longevity claims outrun the evidence — see our evidence review
Visit Drip Hydration ↗Shown for honest comparison · verified on the provider's own site in 2026
7
Tru Niagen
The most evidence-backed oral NAD+ precursor — patented Niagen NR, third-party verified.
About $49 per 30-count bottle (≈$39 on subscription)
An oral capsule delivering 300 mg of patented Niagen nicotinamide riboside (NR) daily — a different approach from injectable NAD+. It is the benchmark of the oral-precursor category: Alkemist Assured third-party verified, ISO/IEC 17025-tested, with multiple human RCTs showing NR meaningfully raises blood NAD+. NR has long-standing GRAS/NDI clearance, so it never faced the NMN regulatory uncertainty.
Strengths
Strongest clinical evidence in the oral category — real RCTs raising blood NAD+
Patented Niagen NR with Alkemist Assured third-party verification
Inexpensive and over-the-counter — no prescription or clinician review needed
Trade-offs
An oral precursor, not a clinician-reviewed Rx injection like CoreAge
Raises NAD+ via NR rather than delivering NAD+ directly; premium price for the dose
Visit Tru Niagen ↗Shown for honest comparison · verified on the provider's own site in 2026
8
Thorne NiaCel 400
Trusted practitioner-grade oral NR — NSF Certified for Sport, widely third-party tested.
Roughly $45–$65 per bottle (varies by retailer)
An oral capsule from Thorne, a practitioner-trusted supplement brand, delivering nicotinamide riboside (as NR malate). NiaCel 400 is NSF Certified for Sport and broadly third-party certified, making it a low-red-flag oral NR pick. Like Tru Niagen it raises NAD+ through a precursor rather than delivering the NAD+ molecule directly, and requires no prescription.
Strengths
NSF Certified for Sport from a widely trusted practitioner brand
Over-the-counter oral NR with no clinician review or membership
Trade-offs
An oral precursor, not a doctor-reviewed Rx injection or nasal protocol
Pricing varies across retailers; NR malate form, and no included support
The honest comparison at a glance. “Flat pricing” means a single all-in monthly figure with no separate membership or lab fee.
Provider
Price
Flat pricing
Consult incl.
Pharmacy
Labs required
Nurse/RD support
1.CoreAge RxFeatured
$93/mo flat
Flat pricing: yes
Consult included: yes
503A
No
Nurse and dietitian support: yes
2.HydraMed
$299/mo
Flat pricing: yes
Consult included: yes
Unspecified
No
Nurse and dietitian support: no
3.AgelessRx
From $185/mo
Flat pricing: no
Consult included: yes
Network
Optional
Nurse and dietitian support: no
4.Invigor Medical
From $340/mo
Flat pricing: no
Consult included: yes
Network
Optional
Nurse and dietitian support: no
5.Hone Health
$165/mo + membership
Flat pricing: no
Consult included: yes
Network
Yes
Nurse and dietitian support: no
6.Drip Hydration
~$799+/session
Flat pricing: no
Consult included: no
Unspecified
No
Nurse and dietitian support: no
7.Tru Niagen
~$49/30ct
Flat pricing: yes
Consult included: no
Unspecified
No
Nurse and dietitian support: no
8.Thorne NiaCel 400
~$45–65
Flat pricing: yes
Consult included: no
Unspecified
No
Nurse and dietitian support: no
Prices and program details were verified on each provider's own site in 2026 and can change without notice. “Optional” labs means the provider may offer or suggest testing but does not gate the basic plan on it. Confirm current terms with the provider before starting.
Why CoreAge Rx ranks first
CoreAge wins on the fundamentals rather than on any claim that NAD+ is a miracle. The price is genuinely flat — $93/month with no membership or lab surcharge to discover later, and the same price covers either the injection or the “Hello Energy” nasal spray. The intake is reviewed by U.S.-licensed clinicians, the protocol is filled by a 503A compounding pharmacy, and every plan includes 1:1 consults with nurses and registered dietitians. If you are not approved, you are refunded automatically.
We are also honest about the science: NAD+'s clinical evidence is modest, and injectable and nasal NAD+ specifically have no rigorous randomized-trial evidence. Compounded NAD+ is not an FDA-approved product. This ranking is about provider quality, value, and experience — not a promise that NAD+ shots boost energy or longevity. Read the full picture in our NAD+ therapy evidence review before deciding.
We do not run sponsored reviews or accept payment to move a provider up the list. Rankings weigh four factors, with price transparency carrying the most weight because hidden recurring fees are the most common way NAD+ programs end up costing more than they first appear.
Price transparency
We reward a single, all-in monthly price. Plans that stack a membership or lab fee on top of the medication price rank lower than a true flat rate.
Clinical oversight
Real review by U.S.-licensed clinicians of an online intake, with a clear path to decline patients who are not appropriate candidates.
Pharmacy quality
We note whether the compounding pharmacy is identified (e.g. a 503A facility) rather than left vague.
Human support
Included access to nurses or registered dietitians — not just a shipped vial — meaningfully improves the experience.
Read the evidence first
A provider ranking is only half the decision. Understand what NAD+ can and cannot do before you start:
This page is informational and not medical advice. NAD+ is available by prescription after clinician review; compounded NAD+ is not FDA-approved, and injectable or nasal NAD+ has no rigorous clinical-trial evidence for energy or longevity. Talk to a licensed provider about whether it is appropriate for you.