provider_review · verified 2026-07-31

RxSpan MD review

Three NAD+ routes, three prices, all on the public homepage

Injection $249, nasal spray $249 and a flex-dose tablet $199, printed as a price list you can read without starting an intake — which is rarer in this category than it should be.

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at_a_glance

price: Homepage price tiles: "Nicotinamide Adenine Dinucleotide (NAD+) Injection — $249", "NAD+ Nasal Spray — $249", "NAD+ Flex Dose Tablet — $199".
what you pay: $249/month for either the injection or the nasal spray, $199 for the tablet, as published. The FAQ states no long-term commitments and no hidden fees.
pharmacy: Four are named in RxSpan's own FAQ, under "Who are your Pharmacy Providers?", each with a phone number and a website: Belmar Pharmacy, Strive Pharmacy, Epiq Scripts and Casa Pharma Rx. The same FAQ block answers "Who is your Medical Team?" with Lion MD — Dr Ana Lisa Carr MD (NPI 1689841744) and Dr Kelly Tenbrink MD (NPI 1346482684), both checkable in the national registry. None of the four pharmacies carries a published 503A or 503B designation, so you know who fills it without knowing under which regulatory regime. Two qualifiers. Those same four pharmacies and those same two clinicians appear on Care Bare Rx, Synergy Rx, Sunlight and Breeze Meds, because all five run on one CareValidate backend — it is real disclosure, published and checkable, but it is shared rather than independent, and one brand's bench is never corroboration for another's. And separately, the only clinician RxSpan names as its own is its founder Dr John Diaz MD (NPI 1295815090), an active PLASTIC SURGEON: no endocrinology, obesity-medicine or age-management credential appears anywhere on the site.
states: No state list published that we could find, and the "all 50 states" this row previously carried came from our own stored record rather than from anything on RxSpan's site, so it is gone. Treat that as weaker evidence than usual rather than a settled negative: RxSpan's FAQ hydrates client-side from its intake backend, which is exactly how an earlier pass of ours wrongly concluded it named no pharmacy. Eligibility is settled at intake.
on our index: Ranked #6 of 50 on our NAD+ provider index.

verdict

The short version

RxSpan MD is the most comparison-shoppable provider on our index. Its homepage prints a full menu with a number beside every item, including three NAD+ routes: injection at $249, nasal spray at $249, and a flex-dose tablet at $199. It names four dispensing pharmacies and its medical team with NPIs, serves all 50 states, and states no long-term commitment and unlimited 24/7 messaging. The price is the problem, not the transparency: $249 is more than two and a half times CoreAge's $93 floor for what is, clinically, the same unproven compounded product. The $199 tablet is the interesting item on the menu, an oral route $50 under RxSpan's own injection — though several providers here sell an injection for less than either figure.

evidence

What the evidence for this route shows

Compounded NAD+ is not an FDA-approved product, and the route sold here has no randomized human trial behind it: there is no published study showing that subcutaneous or intranasal NAD+ raises blood NAD+ in people, let alone that it improves energy, focus or any aging endpoint. What the clinical literature actually supports is the oral precursor NR, which does raise blood NAD+ in controlled trials — a different molecule by a different route. The flex-dose tablet is the exception worth understanding: an oral NAD+ tablet is not the same thing as oral NR, and the human trial evidence sits with NR specifically, not with swallowing NAD+ itself.

pricing

What it actually costs

advertised: Homepage price tiles: "Nicotinamide Adenine Dinucleotide (NAD+) Injection — $249", "NAD+ Nasal Spray — $249", "NAD+ Flex Dose Tablet — $199".
you pay: $249/month for either the injection or the nasal spray, $199 for the tablet, as published. The FAQ states no long-term commitments and no hidden fees.
the catch: None named on the NAD+ line — but read the tile as an entry price rather than a locked rate. On the same site's weight-loss products the identical $249 tile opens onto a plan-length ladder (monthly $249, three-month $219, six-month $199, twelve-month $194) with the card labeled "for the first month". Nothing on the NAD+ tiles says whether the same structure sits behind them.

Other money you will meet

Free expedited delivery, stated on the site
Unlimited 24/7 messaging with the care team, included
No membership fee published

source :: read at rxspanmd.com on 2026-07-31, in a browser that runs JavaScript.

fit

Who this is and is not for

Buy it if

You want to compare a full price list before handing over any personal information
You want an oral flex-dose tablet rather than a needle or a nasal spray
You want the dispensing pharmacies named rather than described as "our network"
You want a single provider covering NAD+ alongside hormones, hair and weight loss

Look elsewhere if

You are price-sensitive: $249 is the top of the prescription range on our index
You want a 503A or 503B designation — four pharmacies are named, none is categorized
You want the lowest per-month cost for the same molecule
You want strong human evidence for injected or intranasal NAD+ — there is none

included

What is inside the price

consult: Yes — physician-led telehealth under Dr. John Diaz, with an online intake reviewed before dispensing.
labs: Not required and not published as a gate for the NAD+ line.
follow-ups: Unlimited 24/7 messaging with the care team is advertised as included, with no per-message or per-visit fee published.
human support: 24/7 messaging with the care team. No dietitian or coaching program is part of the offer.
supplies: Not itemized on the public pricing tiles for the injection.
shipping: Free expedited delivery, stated on the site.

the_knock

What they would rather you skipped

RxSpan MD charges the same $249 for NAD+ that it charges for compounded semaglutide — and $249 is also its price for semaglutide capsules. When a menu prices a fatigue product, an injectable weight-loss drug and an oral weight-loss drug identically, the number is telling you about the shape of the business rather than the cost of the medicine. Set beside that the plan-length ladder documented on the same site's weight-loss funnel, where the headline tile turns out to be a first-month rate against a twelve-month price $55 lower, and the honest reading of the NAD+ tiles is: this is what the first month costs, and the intake decides the rest. Four named pharmacies with no 503A/503B designation is the other gap — naming a pharmacy without naming its category tells a reader who to look up but not what they will find.

And the rest

$249 is 168% above CoreAge's published floor for the same unapproved compounded product
The identical $249 appears against unrelated products across the menu, which reads as menu pricing rather than cost-based pricing
Four pharmacies named, none categorized as 503A or 503B — and the same four, with the same two clinician NPIs, appear on Care Bare Rx, Synergy Rx, Sunlight and Breeze Meds off one shared backend, so the disclosure is real but not independently RxSpan's
The weight-loss side of the same site prices on a plan-length ladder; nothing states whether NAD+ does too

tools

Work out your own number

NAD+ therapy cost calculator

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Every figure on this page was read on RxSpan MD’s own site on 2026-07-31 in a browser that runs JavaScript, and prices change without notice. Compare it against the rest of the field on our NAD+ provider index, or read every provider review.

Medical disclaimer: This content is for general educational purposes only and is not medical advice, diagnosis, or treatment. Always consult a licensed healthcare professional before starting, stopping, or changing any treatment.