Synergy Rx review
Updated
The ladder is inverted — month to month is the cheapest rung
NAD+ is $275 month to month with real discounts at three, six and twelve months, but on the weight-loss side of the same catalog the three-month bundle costs more per month than paying monthly does.
$275/mo
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Key details
- Advertised price
- The Longevity tab prices NAD+ injection at $275, with $525 for three months ($175/mo), $899 for six ($150/mo) and $1,599 for twelve ($133/mo). Sermorelin, glutathione and PT-141 are $275; B-12 is $109.
- Billing details
- $275 a month, month to month. That is the standing rate and the cheapest way to buy a single month — the three prepay rungs are genuine discounts on the longevity line, unlike on the same site's weight-loss line.
- Pharmacy
- Four are named in the homepage FAQ, with phone numbers: Belmar, Strive, Epiq Scripts and Casa Pharma Rx. The medical group is Lion MD, and two prescribing physicians are published with NPIs you can look up — Dr Ana Lisa Carr MD (1689841744) and Dr Kelly Tenbrink MD (1346482684). None of the four pharmacies carries a published 503A or 503B designation, and the entity named on the Terms for medical services is a third name again, Usable Health, PC. The disclosure is real, but it is not Synergy's alone: Breeze Meds, Care Bare Rx and Sunlight publish the same four pharmacies and the same two clinicians, word for word, because the four brands share one platform. One brand's clinicians are never independent proof for another's.
- Availability
- Not published. The Terms say the service is "available to individuals located in certain states" and direct you to contact customer service for the list. Product-level no-ship lists do exist inside the catalog — glutathione, B-12 and the skin creams are excluded from eleven states, and NAD+ in those eleven is filled by a secondary pharmacy at a price that "may vary" — so eligibility and cost are both settled after you ask.
- Comparison
- Listed on our NAD+ provider index.
Our verdict
Synergy Rx has a broad injectable longevity menu — NAD+, sermorelin, glutathione, B-12 and PT-141, each priced separately rather than bundled into an unnamed "program" — and it publishes the whole price ladder instead of hiding it behind an intake. NAD+ is $275 month to month, with prepay options at $175, $150 and $133 a month. $275 is on the high side for NAD+; you are paying for menu breadth more than for the medicine. Two things sit under the numbers, both in the company's own words: its Terms say the final charge "may fluctuate contingent upon the prescribed medication and the chosen pharmacy", so none of these figures is binding; and its About page advertises a Money Back Guarantee that its Terms flatly contradict.
NAD+ evidence
Compounded NAD+ is not an FDA-approved product, and the route sold here has no randomized human trial behind it: there is no published study showing that subcutaneous or intranasal NAD+ raises blood NAD+ in people, let alone that it improves energy, focus or any aging endpoint. What the clinical literature actually supports is the oral precursor NR, which does raise blood NAD+ in controlled trials — a different molecule by a different route. Synergy sells the injectable route only for NAD+, and it also sells glutathione and PT-141 injections, neither of which has the evidence base its own product copy implies — the PT-141 description in particular credits a sexual-function drug with raising growth hormone, which is not what that molecule does.
Pricing and fees
- Advertised price
- The Longevity tab prices NAD+ injection at $275, with $525 for three months ($175/mo), $899 for six ($150/mo) and $1,599 for twelve ($133/mo). Sermorelin, glutathione and PT-141 are $275; B-12 is $109.
- Payment terms
- $275 a month, month to month. That is the standing rate and the cheapest way to buy a single month — the three prepay rungs are genuine discounts on the longevity line, unlike on the same site's weight-loss line.
- Pricing details
- Two, and the second is unusual enough to be worth naming even though it is not on this product. First: the Terms warn that the final charge "may fluctuate contingent upon the prescribed medication and the chosen pharmacy", so every figure above is provisional. Second, on the weight-loss side of the same catalog the ladder is INVERTED — the three-month semaglutide bundle works out to $249 a month against $199 month to month, and the tirzepatide bundle to $356 against $349. A multi-month bundle that costs more per month than not committing is the opposite of the usual trap, and it means "bundle" on this site cannot be read as "discount" without checking.
Additional fees
- Medical consult fees are stated in the Terms as non-refundable, and are never priced on any page
- Glutathione, B-12 and the skin creams are not shipped to eleven states; NAD+ in those states is filled by a secondary pharmacy at a cost the company says "may vary"
- A "$100 welcome credit" and a "2026 Promo Applied!" banner run site-wide with no published terms
- Cash-pay only; all sales are stated as final
Prices are from Synergy Rx's own website and can change without notice.
Who it may suit
May suit you if
- You want NAD+, glutathione and B-12 from one provider with a separate published price for each rather than one bundled figure
- You want the full plan ladder visible before an intake, including the month-to-month option
- You want a standalone B-12 injection at $109
- You plan to prepay: at twelve months the NAD+ rate drops to $133 a month
- You want the dispensing pharmacies and the prescribing physicians named — four pharmacies with phone numbers and two NPIs you can check, in the homepage FAQ
Consider another option if
- You want a binding price — the Terms say the final charge may differ from the published one
- You want to know before buying whether your state is served: Synergy publishes no state list at all
- You want a pharmacy list that is Synergy's own — the four it names are the same four its sister brands on the same platform name, in the same words
- You are price-sensitive at the month-to-month rate: $275 a month is on the high side
What’s included
- Consultation
- Yes — its About page states "Unlimited 24/7 Support Included" with unlimited appointments, messaging and support. The one qualifier is about money, not access: the Terms separately refer to "medical consult fees" that are non-refundable and never price them, so a fee exists somewhere even though appointments are advertised as unlimited.
- Lab testing
- Never mentioned. No lab requirement is published and no page states that labs are unnecessary either.
- Follow-up care
- Included — unlimited appointments are stated on its About page, with no per-visit charge published.
- Clinical support
- Unlimited 24/7 messaging and support with the care team, stated on its About page. No nurse or dietitian program is offered, and this copy is shared with its sister brands on the same platform rather than written for Synergy.
- Supplies
- Not itemized. Synergy's product pages leave out the dose ladder a sister brand on the same platform publishes for the same molecules.
- Shipping
- Not priced on the pages we read.
Limitations and policy details
Synergy Rx's PT-141 product description belongs to a different drug. It says PT-141 "is a peptide that increases the body's natural production of growth hormone," promising lean muscle, less body fat and better sleep — which is the sermorelin copy pasted onto the wrong molecule. PT-141 is bremelanotide, a melanocortin agonist used for sexual dysfunction; it does not raise growth hormone and none of those outcomes belongs to it. We are naming the error and not repeating the claim, because repeating it is how a copy-paste mistake turns into a fact. It matters beyond one product: the same text runs across every brand on this company's shared platform, so you cannot assume any product description here was written about the product it sits under. Add two self-contradictions — an About page advertising a Money Back Guarantee while the Terms say all sales are final and consult fees are non-refundable, and a Terms clause warning that the final charge may differ from the published price — and you get a company whose prices are fully published (a month-to-month rate plus three prepay options) while its written claims are unreliable.
Other considerations
- Its own Terms say the final charge "may fluctuate contingent upon the prescribed medication and the chosen pharmacy", so no published figure binds
- Its About page advertises a "Money Back Guarantee" while the Terms say all sales are final and consult fees are non-refundable
- The PT-141 product description is the sermorelin description on the wrong molecule, crediting a sexual-function drug with raising growth hormone
- No state list is published anywhere; the Terms tell you to phone and ask
- The four pharmacies and two NPIs it lists are the same ones Breeze Meds, Care Bare Rx and Sunlight list — real disclosure, but shared across one platform rather than Synergy's own
- None of the four named pharmacies carries a published 503A or 503B designation
- On the weight-loss side of the same catalog the three- and six-month bundles cost more per month than paying monthly
- Neither the dose nor the strength of the NAD+ injection is published, though a sister brand on the same platform publishes both
- "Join 50,000+ SynergyRx patients" and a permanent "$100 welcome credit" run with no source and no terms
Cost calculators
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Every figure on this page comes from Synergy Rx’s own site, and prices change without notice. Compare it against the rest of the field on our NAD+ provider index, or read every provider review.
Medical disclaimer: This content is for general educational purposes only and is not medical advice, diagnosis, or treatment. Always consult a licensed healthcare professional before starting, stopping, or changing any treatment.