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Trellis Vitality Review: NAD+ From $129 and the Plan Terms

Trellis advertises NAD+ from $129/month. We examine its plan durations, pharmacy disclosure, labs, cancellation and the details still missing from the quote.

By Marcus HaleLongevity Research Editor
Updated

5 min read · 10 sources

On this page

Trellis Vitality advertises subcutaneous NAD+ treatment plans starting at $129 per month. The current page describes monthly, three-month and six-month options, but does not publish the NAD+ price for each duration or connect the $129 floor to a specific plan. Its strongest practical disclosure is a named clinical group and pharmacy; its largest buying limitation is that the displayed number does not establish the total you would pay or the amount of medication supplied. 9

Price and the missing plan details

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Physician-prescribed injectable NAD+, sold as a course rather than a monthly plan

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The current NAD+ offer shows a $129 monthly starting figure with a free clinical-assessment button. The FAQ says longer plans lower the per-month cost, while the terms say prescription and protocol fees are described at checkout. That does not tell us whether $129 applies to one month, a longer commitment, a prepaid total divided into months or another configuration. A different treatment’s pricing cannot resolve the NAD+ offer. 910

The public program page does not disclose the vial concentration, vial volume, total milligrams, prescribed frequency or the number of injections included at that price. Without those details, a cost-per-dose comparison would be invented. On the NAD+ price index, compare a starting figure with other starting figures rather than treating it as a confirmed month-to-month charge.

Before accepting a plan, request its total initial charge, renewal amount and interval, shipment schedule, medication quantity and cancellation effect in writing. For three- or six-month options, ask whether the entire term is charged upfront and what happens to undispensed medication if you stop. The public terms do not settle those questions.

Trellis NAD+ purchase details

Swipe table to compare all columns →

QuestionPublic disclosureWhat to confirm
PriceFrom $129/monthTotal charge and plan duration
Plan lengthMonthly, three months or six monthsUpfront payment and renewal schedule
MedicationSubcutaneous injectionStrength, volume and total milligrams
LabsBaseline and 90-day retest describedRequired panel and included costs
ShippingFree expedited shipping advertisedDispatch timing and handling
RefundsAssessed per orderDeadline, refundable stages and amounts
The starting price is not a complete quote; confirm the full charge and supplied amount.

What the program says it includes

Trellis markets the program around an online assessment, clinician review, baseline labs and medication delivery, with no membership or consultation costs and free expedited shipping. The FAQ also describes a baseline and a 90-day biomarker retest. Those are seller descriptions of its care model, not a verified statement that every lab panel or repeat test is included in the $129 starting plan. The page does not itemize the panel or a separate laboratory fee schedule. Ask which tests are required, what they cost and whether results change the decision to continue treatment. 9

The purchase selector identifies injection. The FAQ also discusses a transdermal patch, but does not publish a separate patch price, strength or supply. Do not assume that the injection’s starting price purchases either route interchangeably. Our injection evidence guide and IV evidence guide explain why each route needs its own evidence.

Pausing, canceling and refunds

The terms identify Trellis Vitality, LLC as the platform operator and say there is no membership requirement, plans differ by duration, and buyers may pause or cancel anytime. They also say refund eligibility is determined per order and direct buyers to customer support. 10

That is more limited than a money-back guarantee. The public terms do not provide a cancellation deadline before a renewal, a pro-rata refund formula, a guaranteed refund if a clinician declines treatment or a precise point at which an order becomes nonrefundable. Cancellation may stop future care without reversing a charge already incurred; confirm the rule for the actual plan before paying. A customer-support decision should not be assumed to be an unconditional refund right.

Clinicians, pharmacy and testing disclosure

The NAD+ FAQ names Arora Health & Aesthetics, LLC, medical director Dr. Sean Arora, and NPI 1841729449. It identifies VialsRX in Houston as the dispensing pharmacy; the current terms additionally publish its address, phone number and website. These are useful identities to confirm against the prescription and shipment paperwork. 910

Trellis says batches undergo potency, sterility, pH and endotoxin checks. The pages reviewed do not provide a lot-specific laboratory report that lets a buyer independently verify the actual dispensed vial. Ask the pharmacy about the assigned lot, beyond-use date, storage instructions and how to report a damaged or questionable shipment. A manufacturing/testing statement and a demonstrated health benefit are separate claims. 9

The site advertises service in all 50 states but qualifies that medications, formulations and fulfillment can vary with state rules. Its terms require adults 18 or older and clinical eligibility. The actual prescribed formulation and delivery address still need confirmation. 10

Trellis and The Edit share a clinical group

Trellis and The Edit both identify Arora Health & Aesthetics and the same medical director. They disclose different pharmacy arrangements and prices, so their commercial offers can be compared. However, they are not independent medical organizations for someone seeking an outside second opinion. Sharing a group does not prove that the same individual clinician would review both applications.

What the science supports

The store’s comparison calls oral precursors low-yield and its injection the highest-yield route. The cited human evidence does not establish that this home subcutaneous protocol provides better energy, focus, recovery or aging outcomes than an oral precursor. The 2019 IV pilot measured plasma and urine metabolism during a six-hour infusion; it did not establish routine wellness benefits, and an IV experiment cannot establish efficacy for this subcutaneous program. 2

Oral NR does have controlled human evidence for raising blood NAD+ 34 and altering the skeletal-muscle NAD+ metabolome 5. The downstream benefits remain less dependable: pooled metabolic outcomes are limited and inconsistent 6, and an NMN trial’s biomarker response does not establish a broad functional payoff 7. A lab number moving is not proof that an injection plan has improved health. The NR value guide compares the less invasive precursor approach.

Before accepting a plan

Get a quote that identifies what $129 buys

  • Confirm which duration earns the $129 starting figure and whether a longer term is prepaid.
  • Obtain the vial concentration, volume, total milligrams and prescribed supply duration.
  • Ask whether baseline and repeat labs are included in the quoted plan.
  • Get the cancellation deadline and refund treatment for a declined, prepared or shipped order.
The published terms allow pausing or canceling, but refunds remain subject to per-order assessment.

Is Trellis Vitality worth considering?

Trellis may suit someone who specifically wants clinician-guided home injections and is willing to obtain a complete written quote before deciding. Its named group and pharmacy and its public acknowledgment that compounded products are not FDA-approved are useful disclosures. The limitation is the combination of a starting price, undisclosed medication quantity and discretionary refund language. The public offer cannot yet support a precise value comparison. 910

For another offer to compare on concentration, quantity and total cost, see our Auren Rx review; for a published $249 monthly offer with different cancellation and fulfillment terms, see The Edit review. The broader decision is whether this route is worth buying at all: is NAD+ therapy worth it? and the NAD+ rankings hub put the offer in context. This is consumer education, not personalized medical advice.

Frequently asked questions

How much does NAD+ cost at Trellis Vitality?

The current product page displays treatment plans starting at $129 per month. It describes monthly, three-month and six-month plans without a NAD+ price for each duration or a confirmed total initial charge. Treat $129 as an advertised floor, not a verified month-to-month quote.

Can I cancel or get a refund from Trellis?

The terms say no membership is required and plans may be paused or canceled anytime. Refund eligibility is determined per order through support. The public terms do not give a renewal cutoff, pro-rata formula or guaranteed decline-stage refund, so request the actual plan rules before paying.

Which pharmacy does Trellis Vitality name?

Its NAD+ FAQ and terms identify VialsRX in Houston. That is the seller’s pharmacy disclosure, not an independent quality certification of your vial. Confirm the dispensing pharmacy, medication label, storage requirements and any available lot documentation for your prescription.

Are Trellis Vitality and The Edit independent clinical options?

Both identify Arora Health & Aesthetics, LLC and medical director Dr. Sean Arora. Their commercial offers and pharmacy arrangements differ, but they share a clinical group. This does not establish that the same individual clinician handles every application; it does mean they are not separate medical organizations for an outside second opinion.

Does Trellis prove injections work better than oral NR?

No such advantage is established by the cited evidence. Oral NR trials support increasing blood NAD+, while the 2019 IV pilot measured metabolism rather than wellness outcomes. Neither that IV study nor seller bioavailability claims establish energy, focus or aging benefits for this home subcutaneous protocol.

References

  1. Trellis Vitality (2026). NAD+, glutathione, lipo-MIC and GLP-1 program pages. Trellis Vitality website.
  2. Grant R, Berg J, Mestayer R, et al. (2019). A Pilot Study Investigating Changes in the Human Plasma and Urine NAD+ Metabolome During a 6 Hour Intravenous Infusion of NAD+. Frontiers in Aging Neuroscience. https://pubmed.ncbi.nlm.nih.gov/31572171/
  3. Trammell SAJ, Schmidt MS, Weidemann BJ, et al. (2016). Nicotinamide riboside is uniquely and orally bioavailable in mice and humans. Nature Communications. https://pubmed.ncbi.nlm.nih.gov/27721479/
  4. Martens CR, Denman BA, Mazzo MR, et al. (2018). Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults. Nature Communications. https://pubmed.ncbi.nlm.nih.gov/29599478/
  5. Elhassan YS, Kluckova K, Fletcher RS, et al. (2019). Nicotinamide Riboside Augments the Aged Human Skeletal Muscle NAD+ Metabolome and Induces Transcriptomic and Anti-inflammatory Signatures. Cell Reports. https://pubmed.ncbi.nlm.nih.gov/31412242/
  6. Oliveira-Cruz A, Macedo-Silva A, Silva-Lima D, et al. (2024). Effects of Supplementation with NAD+ Precursors on Metabolic Syndrome Parameters: A Systematic Review and Meta-Analysis. Hormone and Metabolic Research. https://pubmed.ncbi.nlm.nih.gov/39111741/
  7. Yi L, Maier AB, Tao R, et al. (2023). The efficacy and safety of β-nicotinamide mononucleotide (NMN) supplementation in healthy middle-aged adults: a randomized, multicenter, double-blind, placebo-controlled, parallel-group, dose-dependent clinical trial. GeroScience. https://pubmed.ncbi.nlm.nih.gov/36482258/
  8. U.S. Food and Drug Administration (2026). Warning Letters. FDA.gov. https://www.fda.gov/inspections-compliance-enforcement-and-criminal-investigations/compliance-actions-and-activities/warning-letters
  9. Trellis Vitality (2026). Current NAD+ offer, clinical FAQ and pharmacy disclosure — Trellis Vitality website. Trellis Vitality website.
  10. Trellis Vitality (2026). Terms, payment and per-order refund eligibility — Trellis Vitality website. Trellis Vitality website.

Medical disclaimer: This content is for general educational purposes only and is not medical advice, diagnosis, or treatment. Always consult a licensed healthcare professional before starting, stopping, or changing any treatment.